Pax4^tm1.1Aman
Targeted Allele Detail

Summary

• Symbol: Pax4^tm1.1Aman
• Name: paired box 4; targeted mutation 1.1, Ahmed Mansouri
• MGI ID: MGI:5466350
• Synonyms: Pax4^fl
• Gene: Pax4 Location: Chr6:28442333-28449339 bp, - strand Genetic Position: Chr6, 11.99 cM
• Alliance: Pax4^tm1.1Aman page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192683
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exons 2 through 6 floxed. (J:192683)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax4 Mutation: 26 strains or lines available

References

• Original: J:192683 Kordowich S, et al., Generation of animals allowing the conditional inactivation of the Pax4 gene. Transgenic Res. 2012 Dec;21(6):1215-20
• All: 1 reference(s)