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Tg(Myh6-Erbb2)6Kaga
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-Erbb2)6Kaga
Name: transgene insertion 6, Kathleen Gabrielson
MGI ID: MGI:5461578
Transgene: Tg(Myh6-Erbb2)6Kaga  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Erbb2)6Kaga expresses 1 gene
 
Mutation detailsThis transgene consists of the alpha-myosin heavy chain promoter driving the expression of the rat Erbb2 cDNA followed by a polyadenylation signal from human growth hormone. Two lines were made, 3 and 6. (J:189979)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:189979 Sysa-Shah P, et al., Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice. PLoS One. 2012;7(8):e42805
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory