Scrib^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Scrib^tm1.1Geno
• Name: scribbled planar cell polarity; targeted mutation 1.1, Genoway
• MGI ID: MGI:5449166
• Synonyms: Scribble^flox
• Gene: Scrib Location: Chr15:75919011-75941633 bp, - strand Genetic Position: Chr15, 35.29 cM
• Alliance: Scrib^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190169
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 8 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:190169)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scrib Mutation: 53 strains or lines available

References

• Original: J:190169 Hartleben B, et al., Role of the polarity protein Scribble for podocyte differentiation and maintenance. PLoS One. 2012;7(5):e36705
• All: 9 reference(s)