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St3gal6tm1.1Jxm
Targeted Allele Detail
Nomenclature
Symbol: St3gal6tm1.1Jxm
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 6; targeted mutation 1.1, Jamey Marth
MGI ID: MGI:5445089
Synonyms: St3gal6delta
Gene: St3gal6  Location: Chr16:58468125-58524243 bp, - strand  Genetic Position: Chr16, 34.58 cM, cytoband C1.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189086
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 3. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neo cassette and exon 3. RT-PCR confirmed the absence of transcript expression. (J:189086)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any St3gal6 Mutation:  12 strains or lines available
References
Original:  J:189086 Yang WH, et al., Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands. Blood. 2012 Aug 2;120(5):1015-26
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory