Irx5^tm3Hui
Targeted Allele Detail

Summary

• Symbol: Irx5^tm3Hui
• Name: Iroquois homeobox 5; targeted mutation 3, Chi-Chung Hui
• MGI ID: MGI:5444483
• Synonyms: Irx5^EGFP
• Gene: Irx5 Location: Chr8:93084424-93088084 bp, + strand Genetic Position: Chr8, 44.93 cM
• Alliance: Irx5^tm3Hui page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189007
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: ES cells carrying Irx3^tm3Hui were retargeted to replace exon 1 and exon 2 of this gene with an EGFP cDNA and a pgk-puro cassette, respectively. (J:189007)

Expression

In Mice Carrying this Mutation:

52 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irx5 Mutation: 30 strains or lines available

References

• Original: J:189007 Gaborit N, et al., Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology. Development. 2012 Nov;139(21):4007-19
• All: 9 reference(s)