Ccr2^tm1Mpa
Targeted Allele Detail

Summary

• Symbol: Ccr2^tm1Mpa
• Name: C-C motif chemokine receptor 2; targeted mutation 1, Manolis Pasparakis
• MGI ID: MGI:5444249
• Synonyms: CCR2^fl-eGFP
• Gene: Ccr2 Location: Chr9:123901987-123913594 bp, + strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr2^tm1Mpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189044
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An EGFP with a 5' loxP site was inserted downstream of exon 3. (J:189044)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr2 Mutation: 40 strains or lines available

References

• Original: J:189044 Willenborg S, et al., CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. 2012 Jul 19;120(3):613-25
• All: 6 reference(s)