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Targeted Allele Detail
Symbol: Ccr2tm1Mpa
Name: chemokine (C-C motif) receptor 2; targeted mutation 1, Manolis Pasparakis
MGI ID: MGI:5444249
Synonyms: CCR2fl-eGFP
Gene: Ccr2  Location: Chr9:124101918-124109140 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Germline Transmission:  Earliest citation of germline transmission: J:189044
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 3. An EGFP with a 5' loxP site was inserted downstream of exon 3. (J:189044)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr2 Mutation:  23 strains or lines available
Original:  J:189044 Willenborg S, et al., CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. 2012 Jul 19;120(3):613-25
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory