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Targeted Allele Detail
Symbol: Foxc1tm1.1Tsku
Name: forkhead box C1; targeted mutation 1.1, Tsutomu Kume
MGI ID: MGI:5443919
Synonyms: Foxc1delta
Gene: Foxc1  Location: Chr13:31806691-31810643 bp, + strand  Genetic Position: Chr13, 13.52 cM
Hydrocephalus and eye abnormalities in Foxc1tm1.1Tsku/Foxc1tm1.1Tsku fetuses

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:188816
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsCre-mediated recombination removed the coding sequence from Foxc1tm1Tsku. RT-PCR confirmed the absence of transcript expression in embryos. (J:188816)
Generation of the Foxc1tm1Tsku and Foxc1tm1.1Tsku alleles
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc1 Mutation:  10 strains or lines available
Original:  J:188816 Sasman A, et al., Generation of conditional alleles for Foxc1 and Foxc2 in mice. Genesis. 2012 Oct;50(10):766-74
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory