Grntm1Geno
Targeted Allele Detail
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Symbol: |
Grntm1Geno |
Name: |
granulin; targeted mutation 1, Genoway |
MGI ID: |
MGI:5443907 |
Gene: |
Grn Location: Chr11:102321333-102327635 bp, + strand Genetic Position: Chr11, 66.29 cM
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Alliance: |
Grntm1Geno page
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Germline Transmission: |
Earliest citation of germline transmission:
J:188420
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 4 via homologous recombination.
(J:188420)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Grn Mutation: |
44 strains or lines available
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Original: |
J:188420 Wils H, et al., Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice. J Pathol. 2012 Sep;228(1):67-76 |
All: |
1 reference(s) |
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