About   Help   FAQ
Sec63tm1Som
Targeted Allele Detail
Nomenclature
Symbol: Sec63tm1Som
Name: SEC63-like (S. cerevisiae); targeted mutation 1, Stefan Somlo
MGI ID: MGI:5442171
Synonyms: Sec63flox
Gene: Sec63  Location: Chr10:42761496-42832514 bp, + strand  Genetic Position: Chr10, 22.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188763
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 2 was floxed and an FRT-flanked neo cassette was inserted into IVS2. (J:188763)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sec63 Mutation:  3 strains or lines available
References
Original:  J:188763 Fedeles SV, et al., A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet. 2011 Jul;43(7):639-47
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory