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Prkcshtm1Som
Targeted Allele Detail
Nomenclature
Symbol: Prkcshtm1Som
Name: protein kinase C substrate 80K-H; targeted mutation 1, Stefan Somlo
MGI ID: MGI:5442170
Synonyms: Prkcshflox
Gene: Prkcsh  Location: Chr9:22002988-22014245 bp, + strand  Genetic Position: Chr9, 8.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188763
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 6 and 7 were floxed and an FRT-flanked neo cassette was inserted into IVS7. (J:188763)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkcsh Mutation:  24 strains or lines available
References
Original:  J:188763 Fedeles SV, et al., A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet. 2011 Jul;43(7):639-47
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory