Pdx1<tm1Mgn> Targeted Allele Detail MGI Mouse (MGI:5441573)

Pdx1^tm1Mgn
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Summary

Symbol:	Pdx1^tm1Mgn
Name:	pancreatic and duodenal homeobox 1; targeted mutation 1, Mark A Magnuson
MGI ID:	MGI:5441573
Synonyms:	Pdx1^LCA
Gene:	Pdx1 Location: Chr5:147206907-147212658 bp, + strand Genetic Position: Chr5, 86.84 cM

Mutation
origin

Mutation
description

Allele Type:		Targeted
Mutation:		Insertion
		Mutation details: Areas IV, I, II and III and exon 1 were replaced with a kanamycin cassette flanked by lox71 and lox2272 sites. (J:187872)

Overall scheme for generating the Pdx1^tm1Mgn and Pdx1^tm2Mgn alleles

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Pdx1 Mutation:	35 strains or lines available

References

Original:	J:187872 Potter LA, et al., A recombinase-mediated cassette exchange-derived cyan fluorescent protein reporter allele for Pdx1. Genesis. 2012 Apr;50(4):384-92
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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