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Targeted Allele Detail
Symbol: Xbp1tm3Glm
Name: X-box binding protein 1; targeted mutation 3, Laurie H Glimcher
MGI ID: MGI:5441521
Synonyms: XBP-1floxneo
Gene: Xbp1  Location: Chr11:5520659-5525893 bp, + strand  Genetic Position: Chr11, 3.61 cM
Germline Transmission:  Earliest citation of germline transmission: J:131028
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neo cassette was inserted into intron 1 and an additional loxP site was inserted into intron 2. (J:131028)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xbp1 Mutation:  10 strains or lines available
Original:  J:131028 Hetz C, et al., Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):757-62
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory