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Ndrg2tm1.1Xzg
Targeted Allele Detail
Nomenclature
Symbol: Ndrg2tm1.1Xzg
Name: N-myc downstream regulated gene 2; targeted mutation 1.1, Xizhi Guo
MGI ID: MGI:5441449
Gene: Ndrg2  Location: Chr14:51905271-51914004 bp, - strand  Genetic Position: Chr14, 26.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187603
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed the neo cassette and exons 2 through 6. Western blot analysis confirmed the absence of protein expression in E11.5 embryos. (J:187603)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndrg2 Mutation:  2 strains or lines available
References
Original:  J:187603 Zhu H, et al., Ndrg2 regulates vertebral specification in differentiating somites. Dev Biol. 2012 Sep 15;369(2):308-18
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory