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Mfn1tm1.1Arte
Targeted Allele Detail
Nomenclature
Symbol: Mfn1tm1.1Arte
Name: mitofusin 1; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:5440838
Synonyms: Mfn1loxP
Gene: Mfn1  Location: Chr3:32529465-32579239 bp, + strand  Genetic Position: Chr3, 15.75 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188337
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:188337)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mfn1 Mutation:  10 strains or lines available
References
Original:  J:188337 Lee S, et al., Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet. 2012 Nov 15;21(22):4827-35
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory