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Targeted Allele Detail
Symbol: Setdb1tm1.1Yshk
Name: SET domain, bifurcated 1; targeted mutation 1.1, Yoichi Shinkai
MGI ID: MGI:5440719
Synonyms: Eset CKO, ESET(exons15&16)Flox
Gene: Setdb1  Location: Chr3:95323525-95357202 bp, - strand  Genetic Position: Chr3, 40.74 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:188475
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 15 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 16 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:188475)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Setdb1 Mutation:  13 strains or lines available
Original:  J:188475 Matsui T, et al., Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature. 2010 Apr 8;464(7290):927-31
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.01
The Jackson Laboratory