Tg(Aif1-tTA)54Kftnk
Transgene Detail

Summary

• Symbol: Tg(Aif1-tTA)54Kftnk
• Name: transgene insertion 54, Kenji Tanaka
• MGI ID: MGI:5439166
• Synonyms: Iba1-tTA
• Transgene: Tg(Aif1-tTA)54Kftnk Location: unknown
• Alliance: Tg(Aif1-tTA)54Kftnk page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: A modified 2 kb of the mouse promoter drives microglia-specific expression of a mammalianized tetracycline transactivator (tTA). The modification prevents fusion between the mouse sequence and the mammalianized tTA. Lines 54 and 75 were generated. (J:186771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:186771 Tanaka KF, et al., Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep. 2012 Aug 30;2(2):397-406
• All: 7 reference(s)