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Tg(Aif1-tTA)54Kftnk
Transgene Detail
Nomenclature
Symbol: Tg(Aif1-tTA)54Kftnk
Name: transgene insertion 54, Kenji Tanaka
MGI ID: MGI:5439166
Synonyms: Iba1-tTA
Transgene: Tg(Aif1-tTA)54Kftnk  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsA modified 2 kb of the mouse promoter drives microglia-specific expression of a mammalianized tetracycline transactivator (tTA). The modification prevents fusion between the mouse sequence and the mammalianized tTA. Lines 54 and 75 were generated. (J:186771)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:186771 Tanaka KF, et al., Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep. 2012 Aug 30;2(2):397-406
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/26/2022
MGI 6.21
The Jackson Laboratory