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Il17a/Il17ftm1.1Impr
Targeted Allele Detail
Nomenclature
Symbol: Il17a/Il17ftm1.1Impr
Name: interleukin 17F; targeted mutation 1.1, Immo Prinz
MGI ID: MGI:5438793
Synonyms: Il17af-
Gene: Il17f  Location: Chr1:20777146-20785274 bp, - strand  Genetic Position: Chr1, 6.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187400
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA self-excising floxed neo cassette replaced exon 2 and 3 of Il17a and Il17f. This allele lacks the neo cassette. Cell sorting confirmed the absence of T cells expressing either gene. (J:187400)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il17f Mutation:  10 strains or lines available
References
Original:  J:187400 Haas JD, et al., Development of interleukin-17-producing gammadelta T cells is restricted to a functional embryonic wave. Immunity. 2012 Jul 27;37(1):48-59
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory