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Sh2d1b1tm3Vei
Targeted Allele Detail
Nomenclature
Symbol: Sh2d1b1tm3Vei
Name: SH2 domain protein 1B1; targeted mutation 3, Andre Veillette
MGI ID: MGI:5438032
Gene: Sh2d1b1  Location: Chr1:170277376-170285662 bp, + strand  Genetic Position: Chr1, 76.84 cM, cytoband H2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187430
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
    No details provided
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sh2d1b1 Mutation:  1 strain or line available
References
Original:  J:187430 Dong Z, et al., The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells. Immunity. 2012 Jun 29;36(6):974-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory