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Rab7tm1.2Ywd
Targeted Allele Detail
Nomenclature
Symbol: Rab7tm1.2Ywd
Name: RAB7, member RAS oncogene family; targeted mutation 1.2, Yoh Wada
MGI ID: MGI:5437841
Gene: Rab7  Location: Chr6:87999106-88045270 bp, - strand  Genetic Position: Chr6, 39.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187732
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination of Rab7tm1.1Ywd removes exons 2 and 3 along with the neo cassette. (J:187732)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rab7 Mutation:  101 strains or lines available
References
Original:  J:187732 Kawamura N, et al., Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos. Nat Commun. 2012 Sep 18;3:1071
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory