Fnip1^LPAB.1
Chemically induced Allele Detail

Summary

• Symbol: Fnip1^LPAB.1
• Name: folliculin interacting protein 1; LPAB.1
• MGI ID: MGI:5437714
• Gene: Fnip1 Location: Chr11:54329025-54409061 bp, + strand Genetic Position: Chr11, 32.13 cM
• Alliance: Fnip1^LPAB.1 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: ENU mutagenesis induced a 32 bp deletion that results in a premature stop codon at residue 293. Real-time PCR confirmed the absence of transcript expression. (J:187318)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fnip1 Mutation: 59 strains or lines available

References

• Original: J:187318 Park H, et al., Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development. Immunity. 2012 May 25;36(5):769-81
• All: 5 reference(s)