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Shank2tm1Mgle
Targeted Allele Detail
Nomenclature
Symbol: Shank2tm1Mgle
Name: SH3/ankyrin domain gene 2; targeted mutation 1, Min Goo Lee
MGI ID: MGI:5437479
Gene: Shank2  Location: Chr7:144001928-144424494 bp, + strand  Genetic Position: Chr7, 88.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186718
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shank2 Mutation:  3 strains or lines available
References
Original:  J:186718 Won H, et al., Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature. 2012 Jun 14;486(7402):261-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory