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Acot13tm1Deco
Targeted Allele Detail
Nomenclature
Symbol: Acot13tm1Deco
Name: acyl-CoA thioesterase 13; targeted mutation 1, David E Cohen
MGI ID: MGI:5437122
Synonyms: Them2-
Gene: Acot13  Location: Chr13:24817955-24831489 bp, - strand  Genetic Position: Chr13, 10.69 cM, cytoband A3.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183258
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neo cassette replaced exons 2 and 3. Western blot analusis confirmed the absence of protein expression in the liver, white adipose tissue and muscle. (J:183258)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acot13 Mutation:  6 strains or lines available
References
Original:  J:183258 Kang HW, et al., Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism. FASEB J. 2012 May;26(5):2209-21
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory