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Dpf2tm1.2Grc
Targeted Allele Detail
Nomenclature
Symbol: Dpf2tm1.2Grc
Name: D4, zinc and double PHD fingers family 2; targeted mutation 1.2, Gerald R Crabtree
MGI ID: MGI:5435603
Synonyms: Baf45dF/F
Gene: Dpf2  Location: Chr19:5946544-5962899 bp, - strand  Genetic Position: Chr19, 4.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP-flanked neomycin resistance cassette with TK promoter was introduced into intron 3. Transient Cre expression removed the Neo cassette, leaving a residual intron 3 loxP site. The ES cells were re-targeted to introduce a loxP-flanked neomycin cassette into intron 1. Transient Cre expression excised this neo cassette, leaving exons 2 and 3 flanked by loxP sites. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dpf2 Mutation:  30 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory