Tg(GFAP-Cadm1/EGFP)42Oje
Transgene Detail

Summary

• Symbol: Tg(GFAP-Cadm1/EGFP)42Oje
• Name: Transgene insertion 42, Sergio R Ojeda
• MGI ID: MGI:5435596
• Transgene: Tg(GFAP-Cadm1/EGFP)42Oje Location: unknown
• Alliance: Tg(GFAP-Cadm1/EGFP)42Oje page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Dominant negative, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: Mouse Cadm1 sequence encoding a dominant-negative form of the protein lacking the intracellular domain (EGFP replaced the sequence encoding the intracellular domain) was placed under the control of the human GFAP promoter. (J:174704)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:174704 Sandau US, et al., SynCAM1, a synaptic adhesion molecule, is expressed in astrocytes and contributes to erbB4 receptor-mediated control of female sexual development. Endocrinology. 2011 Jun;152(6):2364-76
• All: 2 reference(s)