About   Help   FAQ
Galnt3tcal
Chemically induced Allele Detail
Nomenclature
Symbol: Galnt3tcal
Name: polypeptide N-acetylgalactosaminyltransferase 3; Familial Tumoural Calcinosis
MGI ID: MGI:5435287
Synonyms: Pebbles, Tcal
Gene: Galnt3  Location: Chr2:66082766-66124994 bp, - strand  Genetic Position: Chr2, 38.99 cM, cytoband C3
Ectopic calcifications, testicular abnormalities, and increased apoptosis in Galnt3tcal/Galnt3tcal mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThese mice were identified in an ENU screen. DNA sequence analysis identified a Galnt3 missense mutation (Trp589Arg). (J:187064)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Galnt3 Mutation:  19 strains or lines available
References
Original:  J:187064 Esapa CT, et al., A Mouse with an N-Ethyl-N-Nitrosourea (ENU) Induced Trp589Arg Galnt3 Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis. PLoS One. 2012;7(8):e43205
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/15/2018
MGI 6.12
The Jackson Laboratory