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Tespa1tm1Lrgl
Targeted Allele Detail
Nomenclature
Symbol: Tespa1tm1Lrgl
Name: thymocyte expressed, positive selection associated 1; targeted mutation 1, Linrong Lu
MGI ID: MGI:5432877
Gene: Tespa1  Location: Chr10:130322852-130362642 bp, + strand  Genetic Position: Chr10, 77.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186446
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exon 2 and 3. Western blot analysis confirmed the absence of protein expression in thymocytes. (J:186446)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tespa1 Mutation:  0 strains or lines available
References
Original:  J:186446 Wang D, et al., Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling. Nat Immunol. 2012 Jun;13(6):560-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory