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Sult2b1tm1Rus
Targeted Allele Detail
Nomenclature
Symbol: Sult2b1tm1Rus
Name: sulfotransferase family, cytosolic, 2B, member 1; targeted mutatioin 1, David Russell
MGI ID: MGI:5432568
Gene: Sult2b1  Location: Chr7:45729981-45759672 bp, - strand  Genetic Position: Chr7, 29.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186536
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace the seven coding exons the sulfotransferase 2B1 (Sult2b1) gene with a cassette containing the neomycin resistance gene and Cre recombinase gene under the control of angiotensin-converting enzyme promoter. This cassette was flanked by loxP sites. Cre-mediated recombination during spermatogenesis removed the inserted cassette leaving one loxP site. (J:186536)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sult2b1 Mutation:  5 strains or lines available
References
Original:  J:186536 Russell D, Targeted mutation of the Sult2b1 gene in mice. MGI Direct Data Submission. 2012;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory