Cirbp^tm1Jfuji
Targeted Allele Detail

Summary

• Symbol: Cirbp^tm1Jfuji
• Name: cold inducible RNA binding protein; targeted mutation 1, Jun Fujita
• MGI ID: MGI:5432527
• Gene: Cirbp Location: Chr10:80001824-80008620 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Cirbp^tm1Jfuji page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186425
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neo cassette replaced all the exons. RT-PCR confirmed the absence of transcript expression in mouse embryonic fibroblasts. (J:186425)

Generation of the Cirbp^tm1Jfuji allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cirbp Mutation: 22 strains or lines available

References

• Original: J:186425 Masuda T, et al., Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10885-90
• All: 16 reference(s)