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Smarcc2tm1.1Grc
Targeted Allele Detail
Nomenclature
Symbol: Smarcc2tm1.1Grc
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; targeted mutation 1.1, Gerald R Crabtree
MGI ID: MGI:5431983
Gene: Smarcc2  Location: Chr10:128459248-128490482 bp, + strand  Genetic Position: Chr10, 76.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin cassette flanked by loxP sites was introduced to intron 2 and a loxP site was inserted in intron 3. Cre-mediated recombination removed the neo cassette and exon 3. This deletion creates a protein frame shift after amino acid 77. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Smarcc2 Mutation:  40 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory