Lpar5^tm1Jch
Targeted Allele Detail

Summary

• Symbol: Lpar5^tm1Jch
• Name: lysophosphatidic acid receptor 5; targeted mutation 1, Jerold Chun
• MGI ID: MGI:5431493
• Gene: Lpar5 Location: Chr6:125044883-125059435 bp, + strand Genetic Position: Chr6, 59.21 cM
• Alliance: Lpar5^tm1Jch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185624
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Most of the coding sequence was replaced with EGFP and a floxed neo cassette. The absence of transcript expression in the thymus, spleen and bone marrow. (J:185624)

Generation of the Lpar5^tm1Jch allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lpar5 Mutation: 28 strains or lines available

References

• Original: J:185624 Lin ME, et al., Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain. J Biol Chem. 2012 May 18;287(21):17608-17
• All: 3 reference(s)