Pmis2^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Pmis2^tm1Osb
• Name: PMIS2 transmembrane protein; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:5429746
• Synonyms: Pmis2^-, Pmis2^tm1Oka
• Gene: Pmis2 Location: Chr7:30370147-30371030 bp, - strand Genetic Position: Chr7, 19.08 cM
• Alliance: Pmis2^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185714
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Both exons were replaced with a neomycin selection cassette. (J:185714)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 8 strains available Cell Lines: 0 lines available
• Carrying any Pmis2 Mutation: 13 strains or lines available

References

• Original: J:185714 Yamaguchi R, et al., Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa. Mol Biol Cell. 2012 Jul;23(14):2671-9
• All: 1 reference(s)