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Gene trapped Allele Detail
Symbol: Cdk7Gt(D032B11)1.1Wrst
Name: cyclin-dependent kinase 7; gene trap D032B11, 1.1, German Gene Trap Consortium
MGI ID: MGI:5429213
Synonyms: Cdk7lox
Gene: Cdk7  Location: Chr13:100697027-100730942 bp, - strand  Genetic Position: Chr13, 53.23 cM
Mutant Cell Line:  D032B11 (GGTC)
Germline Transmission:  Earliest citation of germline transmission: J:183925
Parent Cell Line:  TBV2 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: rFlpROSAbetageo
Mutation detailsFlp mediated recombination inverted the gene trap vector in intron 2 allowing expression of the gene. The gene trap vector has only single FRT and F3 sites. (J:183925)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdk7 Mutation:  124 strains or lines available
Original:  J:183925 Ganuza M, et al., Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. EMBO J. 2012 Apr 13;
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.01
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