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Id2tm1Xdz
Targeted Allele Detail
Nomenclature
Symbol: Id2tm1Xdz
Name: inhibitor of DNA binding 2; targeted mutation 1, Xu-Dong Zhao
MGI ID: MGI:5428940
Synonyms: Id2f, Id2Flox, Id2L
Gene: Id2  Location: Chr12:25093799-25096092 bp, - strand  Genetic Position: Chr12, 8.57 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185426
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exons 1 and 2 floxed. (J:185426)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Id2 Mutation:  6 strains or lines available
References
Original:  J:185426 Niola F, et al., Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol. 2012 May;14(5):477-87
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory