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Hprttm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno
Targeted Allele Detail
Nomenclature
Symbol: Hprttm1(Camk2a-APP*Swe*Lon,-MAPT*P301L*R406W)Geno
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 1, Genoway
MGI ID: MGI:5428335
Synonyms: PLB1
Gene: Hprt  Location: ChrX:52988137-53021659 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180977
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt Mutation:  1264 strains or lines available
References
Original:  J:180977 Platt B, et al., Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1. PLoS One. 2011;6(11):e27068
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory