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Gata4tm1Grg
Targeted Allele Detail
Nomenclature
Symbol: Gata4tm1Grg
Name: GATA binding protein 4; targeted mutation 1, Vidu Garg
MGI ID: MGI:5427934
Synonyms: Gata4 G295Ski
Gene: Gata4  Location: Chr14:63198922-63271692 bp, - strand  Genetic Position: Chr14, 33.24 cM
Growth retardation and a thin myocardium in Gata4tm1Grg/Gata4tm1Grg mice

Show the 9 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185124
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Single point mutation
 
Mutation details
Targeting strategy for generation of Gata4tm1Grg knock-in allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gata4 Mutation:  9 strains or lines available
References
Original:  J:185124 Misra C, et al., Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. PLoS Genet. 2012 May;8(5):e1002690
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory