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Fcgr2btm1.2Sjv
Targeted Allele Detail
Nomenclature
Symbol: Fcgr2btm1.2Sjv
Name: Fc receptor, IgG, low affinity IIb; targeted mutation 1.2, J Sjef Verbeek
MGI ID: MGI:5427927
Synonyms: FcgRIIBB6-
Gene: Fcgr2b  Location: Chr1:170958617-170976547 bp, - strand  Genetic Position: Chr1, 78.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:179175
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed the neo cassette and exons 4 and 5. Flow cytometry confirmed the near absence of protein expression in B cells. (J:179175)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fcgr2b Mutation:  15 strains or lines available
References
Original:  J:179175 Boross P, et al., The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility. J Immunol. 2011 Aug 1;187(3):1304-13
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory