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Pax2tm1.1Gdr
Targeted Allele Detail
Nomenclature
Symbol: Pax2tm1.1Gdr
Name: paired box 2; targeted mutation 1.1, Gregory R Dressler
MGI ID: MGI:5427892
Synonyms: Pax2Egfp
Gene: Pax2  Location: Chr19:44744484-44826310 bp, + strand  Genetic Position: Chr19, 38.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:184878
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn EGFP and FRT-flanked neo cassette were inserted upstream of the coding sequence in exon 1. Flp-mediated recombination removed the neo cassette. (J:184878)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 38 assay results
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax2 Mutation:  37 strains or lines available
References
Original:  J:184878 Soofi A, et al., Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys. Dev Biol. 2012 May 1;365(1):241-50
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory