Il15^m1Hwata
Chemically induced Allele Detail

Summary

• Symbol: Il15^m1Hwata
• Name: interleukin 15; mutation 1, Hiroshi Watarai
• MGI ID: MGI:5426268
• Synonyms: Il15^L117P
• Gene: Il15 Location: Chr8:83058261-83129851 bp, - strand Genetic Position: Chr8, 39.33 cM
• Alliance: Il15^m1Hwata page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a nucelotide substitution (CTT to CCT) that results in the amino acid substitution of proline for leucine at position 117 (L117P). (J:184570)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il15 Mutation: 43 strains or lines available

References

• Original: J:184570 Watarai H, et al., Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines. PLoS Biol. 2012 Feb;10(2):e1001255
• All: 1 reference(s)