Fgf20tm1.1Dor
Targeted Allele Detail
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Symbol: |
Fgf20tm1.1Dor |
Name: |
fibroblast growth factor 20; targeted mutation 1.1, David M Ornitz |
MGI ID: |
MGI:5425761 |
Synonyms: |
Fgf20betaGal, Fgf20lacZ |
Gene: |
Fgf20 Location: Chr8:40732206-40740060 bp, - strand Genetic Position: Chr8, 23.89 cM, cytoband B1.2
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Alliance: |
Fgf20tm1.1Dor page
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Disorganization and loss of sensory cells in the Fgf20tm1.1Dor/Fgf20tm1.1Dor organ of Corti
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:184501
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 1 was replaced with lacZ gene and floxed neo cassette. Cre-mediated recombination removed the neo cassette. RT-PCR confirmed the absence of transcript in the inner ear at E14.5.
(J:184501)
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Generation of the Fgf20tm1.1Dor allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Fgf20 Mutation: |
14 strains or lines available
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Original: |
J:184501 Huh SH, et al., Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal. PLoS Biol. 2012 Jan;10(1):e1001231 |
All: |
21 reference(s) |
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