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Celf4tm1.2Frk
Targeted Allele Detail
Nomenclature
Symbol: Celf4tm1.2Frk
Name: CUGBP, Elav-like family member 4; targeted mutation 1.2, Wayne N Frankel
MGI ID: MGI:5425630
Synonyms: Celf4null
Gene: Celf4  Location: Chr18:25477632-25754157 bp, - strand  Genetic Position: Chr18, 13.92 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181678
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 1 was deleted in the germline by cre-mediated recombination of loxP sites that flanked exon 1. Immunoblot analysis of hippocampus and cerebral cortex indicate that no detectable protein is expressed from this allele in homozygous mice. (J:181678)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Celf4 Mutation:  10 strains or lines available
References
Original:  J:181678 Wagnon JL, et al., Etiology of a genetically complex seizure disorder in Celf4 mutant mice. Genes Brain Behav. 2011 Oct;10(7):765-77
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory