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Smarcal1tm1Cfbo
Targeted Allele Detail
Summary
Symbol: Smarcal1tm1Cfbo
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; targeted mutation 1, Cornelius F Boerkoel
MGI ID: MGI:5425306
Synonyms: Smarcal1loxP
Gene: Smarcal1  Location: Chr1:72622410-72672293 bp, + strand  Genetic Position: Chr1, 36.72 cM
Alliance: Smarcal1tm1Cfbo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183899
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. (J:183899)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smarcal1 Mutation:  47 strains or lines available
References
Original:  J:183899 Baradaran-Heravi A, et al., Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression. Hum Mol Genet. 2012 Jun 1;21(11):2572-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory