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Targeted Allele Detail
Symbol: Smarcal1tm1.1Cfbo
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; targeted mutation 1.1, Cornelius F Boerkoel
MGI ID: MGI:5425295
Synonyms: Smarcal1del
Gene: Smarcal1  Location: Chr1:72583251-72633134 bp, + strand  Genetic Position: Chr1, 36.72 cM
Germline Transmission:  Earliest citation of germline transmission: J:183899
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed exons 2 and 3 and the neo cassette. (J:183899)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smarcal1 Mutation:  34 strains or lines available
Original:  J:183899 Baradaran-Heravi A, et al., Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression. Hum Mol Genet. 2012 Jun 1;21(11):2572-87
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory