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Inhbbtm1Grid
Targeted Allele Detail
Nomenclature
Symbol: Inhbbtm1Grid
Name: inhibin beta-B; targeted mutation 1, Tom Gridley
MGI ID: MGI:5319783
Synonyms: BetaBdelta1
Gene: Inhbb  Location: Chr1:119415465-119422248 bp, - strand  Genetic Position: Chr1, 52.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:19647
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.3 kb genomic fragment encompassing about 60% (69 of 115 amino acids) of the coding sequence was replaced with a neo cassette via homologous recombination. (J:19647)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Inhbb Mutation:  17 strains or lines available
References
Original:  J:19647 Schrewe H, et al., Mice homozygous for a null mutation of activin beta B are viable and fertile. Mech Dev. 1994 Jul;47(1):43-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory