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Fstl3tm1.1Sjl
Targeted Allele Detail
Nomenclature
Symbol: Fstl3tm1.1Sjl
Name: follistatin-like 3; targeted mutation 1.1, Sejin Lee
MGI ID: MGI:5319700
Gene: Fstl3  Location: Chr10:79777274-79782630 bp, + strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:182827
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 5 via homologous recombination. Cre mediated recombination deleted exons 3 - 5 and the neo cassette. (J:182827)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fstl3 Mutation:  3 strains or lines available
References
Original:  J:182827 Lee SJ, et al., Regulation of muscle mass by follistatin and activins. Mol Endocrinol. 2010 Oct;24(10):1998-2008
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory