Tigartm1.1Smat
Targeted Allele Detail
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Symbol: |
Tigartm1.1Smat |
Name: |
Trp53 induced glycolysis regulatory phosphatase; targeted mutation 1.1, Satoaki Matoba |
MGI ID: |
MGI:5319186 |
Synonyms: |
TIGARfl |
Gene: |
Tigar Location: Chr6:127062079-127086520 bp, - strand Genetic Position: Chr6, 61.92 cM
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Alliance: |
Tigartm1.1Smat page
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed.
(J:183674)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tigar Mutation: |
54 strains or lines available
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Original: |
J:183674 Hoshino A, et al., p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia. J Mol Cell Cardiol. 2012 Jan;52(1):175-84 |
All: |
2 reference(s) |
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