Gt(ROSA)26Sortm1.1(CAG-COX8A/Dendra2)Dcc
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1.1(CAG-COX8A/Dendra2)Dcc |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, David C Chan |
MGI ID: |
MGI:5318241 |
Synonyms: |
Gt(ROSA)26Sortm1.1(CAG-Mito-Dendra2)Dcc, mito-Dendra2, PhAMexcised |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1.1(CAG-COX8A/Dendra2)Dcc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:183305
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Reporter) |
Mutation: |
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Insertion
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Mutation details: Dendra2 (a green to red irreversibly photoswitchable monomeric fluorescent protein derived from octocoral Dendronephthya sp.) fused to the mitochondrial targeting signal of subunit VIII of cytochrome c oxidase (mito-Dendra2), bovine growth hormone (bGH) polyadenylation signal, and an FRT-flanked neomycin cassette were introduced to Gt(ROSA)26Sor downstream of a CAG (CMV-beta-actin) promoter and loxP-flanked termination signal. Flp-mediated recombination removed the neo cassette and cre-mediated recombination excised the floxed termination cassette.
(J:183306, J:189358)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:183306 Chan DC, Direct Data Submission 2012/05/14. MGI Direct Data Submission. 2012; |
All: |
26 reference(s) |
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