Sik3^tm1Htake
Targeted Allele Detail

Summary

• Symbol: Sik3^tm1Htake
• Name: SIK family kinase 3; targeted mutation 1, Hiroshi Takemori
• MGI ID: MGI:5317918
• Gene: Sik3 Location: Chr9:45924118-46135492 bp, + strand Genetic Position: Chr9, 25.36 cM
• Alliance: Sik3^tm1Htake page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182752
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo cassette replaces exon 1. (J:182752, J:183827)

Expression

In Structures Affected by this Mutation:

23 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sik3 Mutation: 71 strains or lines available

References

• Original: J:182752 Sasagawa S, et al., SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice. Development. 2012 Mar;139(6):1153-63
• All: 7 reference(s)