Lclat1^tm1Arai
Targeted Allele Detail

Summary

• Symbol: Lclat1^tm1Arai
• Name: lysocardiolipin acyltransferase 1; targeted mutation 1, Hiroyoki Arai
• MGI ID: MGI:5317904
• Gene: Lclat1 Location: Chr17:73414980-73550363 bp, + strand Genetic Position: Chr17, 44.79 cM
• Alliance: Lclat1^tm1Arai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183129
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was replaced with a neo cassette. Western blot analysis confirmed the absence of protein expression in the liver. (J:183129)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lclat1 Mutation: 24 strains or lines available

References

• Original: J:183129 Imae R, et al., LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. J Lipid Res. 2012 Mar;53(3):335-47
• All: 1 reference(s)