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Targeted Allele Detail
Symbol: Tmem259tm1.1Itl
Name: transmembrane protein 259; targeted mutation 1.1, inGenious Targeting Laboratory
MGI ID: MGI:5317185
Synonyms: ORF61tm2Zhang
Gene: Tmem259  Location: Chr10:79812954-79820159 bp, - strand  Genetic Position: Chr10, 39.72 cM
Germline Transmission:  Earliest citation of germline transmission: J:183006
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP/FRT site flanked targeting vector containing PGK-Neo selection cassette was utilized in the construction of this allele. This selection cassette was inserted upstream of exon 2 of the targeted gene, and another loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette. (J:183006)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tmem259 Mutation:  12 strains or lines available
Original:  J:183006 Zhang D, Direct Data Submission 2012/05/03. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory