About   Help   FAQ
Chemically induced Allele Detail
Symbol: b2b913Clo
Name: Mutant line 913; Bench to Bassinet Program (B2B/CvDC), mutation 913 Cecilia Lo
MGI ID: MGI:5316782
Gene: b2b913Clo  Location: unknown  
Small right ventricle (RV) and hypoplastic pulmonary trunk in mutant 913-005-NA

Show the 9 phenotype image(s) involving this allele.

Strain of Origin:  C57BL/6J
Project Collection: B2B/CvDC
Allele Type:    Chemically induced (ENU)
Mutation:    Undefined
    This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. Additional incidental mutations were detected in sequencing for the causative mutation, b2b913Clo, and may be present in stocks carrying this mutation.
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any b2b913Clo Mutation:  1 strain or line available
Summative Diagnosis:
Phenotype 1: Cardiovascular defects: Hypoplastic right heart syndrome (HRHS): Hypoplastic right ventricle (RV) with hypoplastic tricuspid valve, and hypoplastic pulmonary trunk.
Phenotype 2: Cardiovascular defects: Ventricular hypertrophy.

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
1720 Hypoplastic tricuspid valve
1821 Hypoplastic right ventricle (subnormal cavity volume)
3608 Left ventricular hypertrophy
3609 Right ventricular hypertrophy

Original:  J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-15;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.20
The Jackson Laboratory